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1:50
The PI3K Signaling Pathway
Genentech BioOncology is currently conducting research on how PI3K Kinase signaling pathway is critical to cell survival and cell growth. Learn how the PI3K pathway involves an intricate signaling cascade that is among the most frequently activated pathways in cancer.
YouTube
Genentech
143.1K views
Nov 13, 2012
Phosphoinositide 3-kinase PI3K Signaling Pathway
SOLVED: Receptor tyrosine kinases (RTKs) can activate multiple signaling pathways. The PI3 kinase' pathway is diagrammed below: You express green fluorescently labeled Akt (GFP-Akt) in cells. Under which of the following conditions would you expect to see fluorescence in the cytoplasm? Choose all that apply Ligand Activated RTKAclivated AktPI3KActivated Bcl2Protein KinasePI 3-kinaseBadBadBclzInactive Bcl2Cell SurvivalBad mutant that cannot be phosphorylated; with ligandWild-type cell; with ligan
numerade.com
Jul 24, 2022
PI3K/mTOR/AKT Signaling Pathway
jove.com
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Consider a signaling pathway that proceeds through three protein kinases that are sequentially activated by phosphorylation. In one case, the kinases are held in a signaling complex by a scaffolding protein; in the other, the kinases are freely diffusible (Figure Q 15-1 ). Discuss the properties of these two types of organization in terms of signal amplification, speed, and potential for cross-talk between signaling pathways. | Numerade
numerade.com
Jun 7, 2020
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