The 49ers might need to be in panic mode after their ugly late fourth quarter loss to the Cardinals. Here's why.

At Lumen Field on Thursday, Jordan Mason and the San Francisco 49ers play Geno Smith and the Seattle Seahawks in a battle ...

Driving into the red zone hasn’t been a problem early this season for the San Francisco 49ers, who have gotten past the ...

The 49ers entered this game with 14 sacks as a team captained by former Defensive Player of the Year Nick Bosa. On the flip side, the Cardinals offensive line had surrendered 10 sacks and a seemingly ...

Ron Wolfley, host of Arizona Sports' Wolf & Luke, got a mohawk on Tuesday because he said he would if the Cardinals beat the 49ers on Sunday.

One of the biggest surprises of the San Francisco 49ers' disappointing 2-3 start has been in the secondary. While Deommodore ...

Here's an early look at the game: TV Channel: Fox (Channel 6 in Milwaukee, Channel 11 in Green Bay) O/U: 49.5 Packers coach ...

The Seattle Seahawks opened this season with three consecutive wins under first-year head coach Mike Macdonald. They've now ...

The 49ers have chosen Matthew Wright to fill in for injured kicker Jake Moody ahead of Thursday’s game at Seattle.

Trystan Colon is set to take over for Will Hernandez at right guard, even though fans probably want to see Jon Gaines or ...

The 49ers lost second-year kicker Jake Moody during a devastating defeat in Week 5 and will bring in a veteran to replace him ...

After going 0-6 in the NFC West a year ago, the Arizona Cardinals have started 2-0 in the division and that could end up ...