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March Madness upset predictions 2025: Which 12 seed is most likely to win in first round?
The 5-12 upset is the most popular NCAA first-round pick, and for good reason. Colorado State leads this year's group of 12-seed upstarts as an outright favorite to beat its 5-seed opponent.
Sporting News on MSN1h
March Madness bracket busters 2025: The best sleeper picks, upset predictions for NCAA Tournament
How do you spot a bracket buster? Last year, eight teams with a double-digit seed won in the first round of the NCAA ...