This is the first conference meeting between the ACC newcomers. The Mustangs are off to a strong start and are trying to maintain their perfect conference record. The Cardinal have lost three straight games by a combined total of 92 points and seek their first home win in the ACC.

When Stanford and SMU were part of the ACC's westward expansion last year, they were set up as annual rivals in football in a plan to cut down on coast-to-coast trips.

Having successfully dealt with two of their new rivals to the east, SMU turns its attention west when the No. 21 Mustangs make their first Atlantic Coast Conference trip to

It is time to continue our college football odds series with a SMU-Stanford prediction and pick. Find out how to watch SMU-Stanford. SMU began the season as a 27.5-point favorite over Nevada in the so-called “Week Zero” weekend of August 24,