Computational models of the glucoregulatory system constitute a powerful tool for preclinical evaluation and mechanistic insight into therapeutics. However, in the case of diabetes, there is a dearth ...

The technological development of naturally occurring gas hydrates and related scientific research require safe and efficient field operations carried out by engineers. Scientific knowledge obtained in ...

The high clinical failure rate of small-molecule drugs is inarguably attributable to the lack of reliable predictions of chemical structure–efficacy–toxicity relationships that are applicable to ...

Low loose bulk density, a characteristic commonly observed in large accumulations of needle-like crystals, has caused numerous issues in both production processes and daily life. Antisolvent ...

ConspectusPhotovoltaics (PVs) are currently the most economical and location-independent source of electricity generation, and their demand is growing rapidly as a sustainable renewable energy source.

In this study, we report the development of a wearable tattoo sticker designed for rapid and noninvasive detection of γ-hydroxybutyrate (GHB), which is commonly associated with drug-facilitated sexual ...

We report an iridium-catalyzed asymmetric formal [3 + 2] cycloaddition between carboxylic acids and vinylcyclopropanes to access highly enantioenriched tetrahydrofurans. This reaction proceeds under ...

Disinfection byproducts (DBPs) are formed during drinking water treatment from the reaction of chemical disinfectants with natural organic matter (NOM), anthropogenic contaminants, and inorganic ...

Pt-based binary intermetallic materials have been a main driver advancing electrocatalysis of fuel cell electrode reactions. Incorporating a third element into binary compositions has proven effective ...

Microorganisms require iron acquisition, particularly in the form of Fe3+ ions from the external environment, for survival. Siderophores are low-molecular-weight compounds secreted by microorganisms ...

Prostate cancer is a common male malignancy. Although androgen deprivation therapy (ADT) is initially effective, it often leads to castration-resistant prostate cancer (CRPC) eventually.

Triple-negative breast cancer (TNBC) is a highly aggressive malignancy lacking targeted therapeutic modalities. Aptamers are promising targeting agents with high specificity and affinity. In this ...